103-04 ScienCell 重組人B細(xì)胞激活因子 rhBAFF,Recombinant Human B Cell Activating Factor
ScienCell 研究實(shí)驗(yàn)室(ScienCell)是一家生物技術(shù)公司,其使命是實(shí)驗(yàn)和治療用細(xì)胞和細(xì)胞相關(guān)產(chǎn)品的研究和發(fā)展。 ScienCell為研究界提供各種高質(zhì)量的正常的人類(lèi)和動(dòng)物細(xì)胞,細(xì)胞培養(yǎng)基和試劑,培養(yǎng)基添加因子,細(xì)胞來(lái)源的RNA,cDNA和蛋白質(zhì)。ScienCell的科學(xué)家們以改善生活質(zhì)量,實(shí)現(xiàn)細(xì)胞的能力,打擊人類(lèi)退化性疾病為目的研究和開(kāi)發(fā)各種細(xì)胞治療策略。ScienCell總部設(shè)在美國(guó)加利福尼亞州圣地亞哥,公司成立于1999年。
北京諾博萊德作為ScienCell品牌的特約經(jīng)銷(xiāo)商,為客戶提供,正規(guī)進(jìn)口,貨期穩(wěn)定,折扣好的服務(wù)標(biāo)準(zhǔn)。
103-04 ScienCell重組人B細(xì)胞激活因子 rhBAFF,Recombinant Human B Cell Activating Factor,產(chǎn)品簡(jiǎn)介:
產(chǎn)品品牌; ScienCell
產(chǎn)品貨號(hào):103-04
產(chǎn)品名稱:103-04 ScienCell重組人B細(xì)胞激活因子 rhBAFF,Recombinant Human B Cell Activating Factor
產(chǎn)品規(guī)格:5ug
ScienCell提供純化的、高質(zhì)量的生長(zhǎng)因子,為您的研究助力。一些專(zhuān)門(mén)的信號(hào)分子,在細(xì)胞的增殖和分化中發(fā)揮核心作用。只有高純度的因子才能實(shí)現(xiàn)信號(hào)通路的高強(qiáng)度活化。 ScienCell提供的生長(zhǎng)因子具有以下特性:高活性,少量的蛋白即有很強(qiáng)效應(yīng);高純度,污染物少,干擾小。
103-04 ScienCell重組人B細(xì)胞激活因子 rhBAFF,Recombinant Human B Cell Activating Factor, 產(chǎn)品說(shuō)明:
B細(xì)胞活化因子(BAFF)是TNF配體超家族成員,由巨噬細(xì)胞,樹(shù)突狀細(xì)胞和T淋巴細(xì)胞產(chǎn)生。BAFF促進(jìn)B細(xì)胞的存活,對(duì)B細(xì)胞成熟至關(guān)重要。BAFF與三個(gè)TNF受體超家族成員結(jié)合:B細(xì)胞成熟抗原(BCMA / TNFRSF17),跨膜激活劑和鈣調(diào)節(jié)劑以及親環(huán)蛋白配體相互作用子(TACI / TNFRSF13B)和BAFF受體(BAFF R / BR3 / TNFRSF 13C)。這些受體是缺乏信號(hào)肽的III型跨膜蛋白。雖然TACI和BCMA結(jié)合BAFF和另一個(gè)TNF超家族配體APRIL(一種增殖誘導(dǎo)配體),BAFF R選擇性結(jié)合BAFF。BAFF R細(xì)胞外結(jié)構(gòu)域缺乏TNF受體典型的富含半胱氨酸的結(jié)構(gòu)域(CRD),并且僅包含具有四個(gè)αysteine殘基的部分CRD。人類(lèi)和小鼠BAFF R共享56%的身份。BAFF R在脾臟、淋巴結(jié)和靜息B細(xì)胞中高表達(dá)。它也在活化的B細(xì)胞,靜息CD4 + T細(xì)胞,胸腺和外周血白細(xì)胞中以較低的水平表達(dá)。
B-cell activating factor (BAFF) is a TNF ligand superfamily member and is produced by macrophages, dendritic cells, and T lymphocytes. BAFF promotes the survival of B cells and is essential for B cell maturation. BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF 13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL(a proliferation-inducing ligand), BAFF R selectively binds BAFF. The BAFF R extracellular domain lacks the TNF receptor canonical cysteine-rich domain (CRD) and contains only a partial CRD with four αysteine residues. Human and mouse BAFF R share 56% identity. BAFF R is highly expressed in spleen, lymph node and resting B cells. It is also expressed at lower levels in activated B cell, in resting CD4+ T cells, in thymus and peripheral blood leukocytes.
ScienCell生長(zhǎng)添加物產(chǎn)品訂購(gòu)信息:
102-01 重組人干細(xì)胞因子 rhSCF,Recombinant Human Stem Cell Factor 2ug
102-02 重組人粒細(xì)胞集落刺激因子 rhG-CSF,Recombinant Human Granulocyte Colony Stimulating Factor 2ug
102-03 重組人粒細(xì)胞巨噬細(xì)胞集落刺激因子 rhM-CSF,Recombinant Human Granulocyte Macrophage Colony Stimulating Factor 5ug
102-09 重組人巨噬細(xì)胞集落刺激因子 rhM-CSF,Recombinant Human Macrophage Colony Stimulating Factor 2ug
103-01 重組人腫瘤壞死因子-alpha rhTNF-α,Recombinant Human Tumor Necrosis Factor-alpha 10ug
103-01H 重組人腫瘤壞死因子-alpha,rhTNF--His,Recombinant Human Tumor Necrosis Factor-alpha, His 10ug
103-01v 重組人腫瘤壞死因子-alpha,Variant rhTNF-α variant,Recombinant Human Tumor Necrosis Factor-alpha Variant 10ug
103-04 重組人B細(xì)胞激活因子 rhBAFF,Recombinant Human B Cell Activating Factor 5ug
103-08 重組人制瘤素-M227a.a. rhOSM,Recombinant Human Oncostatin-M 227a.a. 2ug
103-08T 重組人制瘤素-M209a.a.,Recombinant Human Oncostatin-M209a.a 2ug
103-09 重組人血管生成抑制因子K1-3 rhAngiostatin K1-3,Recombinant Human Angiostatin K1-3 10ug
103-12 重組人血管內(nèi)皮抑制素 rhEndostatin,Recombinant Human Endostatin 20ug
104-01 重組人成纖維細(xì)胞生長(zhǎng)因子-acidic rhaFGF,Recombinant Human Fibroblast Growth Factor-acidic 10ug
104-02 重組人成纖維細(xì)胞生長(zhǎng)因子-basic rhbFGF,Recombinant Human Fibroblast Growth Factor-basic 10ug
104-07 重組人角質(zhì)細(xì)胞生長(zhǎng)因子 rhKGF-1,Recombinant Human Keratinocyte Growth Factor-1 2ug
104-09 重組人成纖維細(xì)胞生長(zhǎng)因子-9 rhFGF-9,Recombinant Human Fibroblast Growth Factor-9 5ug
104-10 重組人角質(zhì)細(xì)胞生長(zhǎng)因子-2 rhKGF-2,Recombinant Human Keratinocyte Growth Factor-2 5ug
104-19 重組人成纖維細(xì)胞生長(zhǎng)因子-19 rhFGF-19,Recombinant Human Fibroblast Growth Factor-19 5ug
104-21 重組人成纖維細(xì)胞生長(zhǎng)因子-21 rhFGF-21,Recombinant Human Fibroblast Growth Factor-21 5ug
105-01 重組人胰島素生長(zhǎng)因子-1 rhIGF-1,Recombinant Human IGF-I 20ug
105-01B 重組人DES(1-3)胰島素生長(zhǎng)因子-1 rhIGF-BP3,Recombinant Human DES (1-3) IGF-1 20ug
105-01B3重組人胰島素生長(zhǎng)因子-BP3,Recombinant Human IGF-BP3 5ug
105-03 重組人longR3胰島素生長(zhǎng)因子-1 rhLR3IGF-1,Recombinant Human Long R3 Insulin-like Growth Factor-1 20ug
105-04 重組人表皮生長(zhǎng)因子 rhEGF,Recombinant Human Epidermal Growth Factor, 100 ug 100ug
105-05 重組人血管內(nèi)皮生長(zhǎng)因子-165 rhVEGF165,Recombinant Human VEGF165 2ug
106-06 重組人干擾素γ rhIFN-γ,Recombinant Human Interferon-gamma 20ug
107-04 重組人神經(jīng)營(yíng)養(yǎng)蛋白-4 rhNT-4,Recombinant Human Neurotrophin-4 2ug
107-08 重組人纖毛神經(jīng)營(yíng)養(yǎng)因子 rhCNTF,Recombinant Human Ciliary Neurotrophic Factor 5ug
107-10 重組人神經(jīng)調(diào)節(jié)蛋白 rhBTC,Recombinant Human NRG-1 EGF-like domain 10ug
107-11 重組人ErbB3片段 rhErbB3-f,Recombinant Human ErbB3 Fragment 5ug
107-12 重組人β動(dòng)物纖維 rhBTC,Recombinant Human Betacellulin 5ug
108-02 重組人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2 2ug
108-04 重組人骨形成蛋白-4 rhBMP-4,Recombinant Human Bone Morphogenetic Protein-4 2ug
108-07 重組人骨形成蛋白-7 rhBMP-7,Recombinant Human Bone Morphogenetic Protein-7 2ug
108-08 重組人骨保護(hù)素 rHuOPG-Fc,Recombinant Human Osteoprotegerin/Fc Chimera 10ug
108-09 重組人NOGGIN蛋白 rhNOGGIN,Recombinant Human NOGGIN 5ug
301-01 重組人生長(zhǎng)激素 rhGF,Recombinant Human Growth Hormone 20ug